Welcome to Pathogenic - A Roguelike Shooter Like No Other
Pathogenic is an exciting 2D roguelike shooter with smooth dual-joystick controls, now available on Android. What truly sets it apart is its bold twist on traditional action games-you don't play the hero. Instead, you step into the role of a pathogen, fighting to survive and evolve inside the human body. This fresh perspective delivers a thrilling and unconventional gameplay experience that feels both innovative and intense.
About Pathogenic
Pathogenic is a fast-paced roguelike action game where you play as a microscopic organism battling immune cells inside the human body. With evolving abilities, strategic organelle upgrades, and unpredictable environments, it offers a unique and challenging survival experience.
Download Pathogenic today and begin your infection-run adventure. Adapt, evolve, and conquer the body from within this new year!
A Microscopic Battlefield with Massive Action
The game takes place within a vibrant, living micro-battlefield where every encounter matters. You control a parasitic organism navigating through complex internal environments while facing relentless waves of immune defences. Each run feels dynamic and unpredictable, as the human body constantly adapts to eliminate you. This ever-changing setting keeps the action fast, challenging, and deeply engaging.
Evolve, Adapt, and Overcome
At the heart of Pathogenic lies its evolution-driven gameplay. As you progress, you unlock and upgrade organelles that enhance your abilities, weapons, and survival strategies. Every decision shapes your build, allowing you to adapt to new threats and experiment with powerful combinations. This strategic layer adds depth, rewarding both quick reflexes and smart planning.
Roguelike Mechanics That Keep Every Run Fresh
True to the roguelike genre, no two runs in Pathogenic are the same. Procedurally generated encounters, varied biomes, and evolving enemy patterns ensure constant variety. Even failure becomes part of the fun, as each run teaches you something new and encourages experimentation with different builds and playstyles.
Bio-Inspired Design and Intense Combat
Pathogenic's bio-inspired visuals and sound design bring the microscopic world to life. From pulsing environments to uniquely designed immune enemies, the game blends science-inspired aesthetics with fast-paced shooter combat. The result is an immersive experience that feels both visually striking and mechanically satisfying.
A major update has been released this new year
Biweekly Update 3.0 - The Swarm
Greetings, fellow parasites!
This update introduces a brand-new summoning playstyle. Tired of being outnumbered? Now you are the swarm.
New Weapon & Organelles
Nidublast - Spawn minions and overwhelm enemies.
New Organelles include:
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Swarm Nidus - Fast, weak ranged minions.
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Apex Nidus - One powerful melee minion
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Galvanic Weave / Infuser - Lightning arcs between enemies
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Toxic - Toxic trails on attacks
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Necrolytic Igniter - Explosions from enemy gibs
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Sinoatrial Node - Bonus damage when attacking on the beat
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Elusive / Metabolic Mitochondrion - Gain overcharge by dodging or looting
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Vacuole - Stores and releases overcharge when needed
Specialised Skill Trees
Each pathogen now has its own plasmid skill tree, allowing deeper customisation and distinct playstyles.
Holiday Bonus
Festive immune cells with Santa hats-don't worry, you're still invited to crash the party.
Teaser
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Sneak peek at the intestinal biome.
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Updated editor visuals
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More stunning art from Roberto
Patch Highlights
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New content + major balance tweaks
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Improved overcharge, beams, and lightning homing
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UI refresh and controller improvements
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Visual upgrades across rooms
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Music cleanup for stomach fight
Biweekly Update 2.0 - High Voltage
Welcome back! Two weeks, one shocking update. This patch brings new weapons, new organelles, loot changes, UI upgrades, balance tweaks, and improved music.
New Additions
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Weapons: Galvanic Conduit (electric discharge), Conductive Cnidocyst (links enemies to share damage)
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Internal Organelles: Galvanic Sac, Sentry Polyp, Golgi Apparatus, Dorasal Lysosome, Cryptobiotic Core, Resilinoplast
Gameplay & Loot
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Cursed Chests added - big rewards, risky cost.
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Special rooms now require payment.
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DNA drops from enemies, not room clears
Visuals, Audio & UI
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Organelle visuals reworked to better reflect evolution.
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Music cleaned up, extended, and more intense.
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Photo Mode added (press P)
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Speedrun Timer added + official speedrun.com page.
Balance & Performance
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Organism chaining reworked to prevent infinite cycles.
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Multiple buffs and nerfs for better build balance
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Improved crash detection and overall optimisation
Plug in, power up, and evolve smarter.
Biweekly Update 01 - More Firepower
Hi everyone,
Pathogenic's demo now receives biweekly updates, starting today with a big content drop! This patch introduces new weapons, organelles, and an enemy, plus balance tweaks, optimisations, and visual improvements.
New Weapons
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Dehiscence Lobber - High-damage bombs (watch the friendly fire!)
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Cnidocyst - Tethers enemies with a binding thread
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Rotary Extruder - Rapid-fire bullets when overcharged
New Internal Organelles
11 new organelles added to expand and build synergies, including Magnetosome, Sympathetic Detonator, Autophagic Mitochondrion, and more.
New Enemy
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Wave Macrophage - AOE-focused enemy found mainly in the Stomach; dangerous in tight spaces.
Gameplay & Balance
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Chronosome now works with melee.
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Reduced explosion and enemy HP scaling
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Easier early rooms and toned-down difficult liver encounters
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Improved cleanup after bosses and rooms
Optimizations & Visuals
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Controller remapping, rumble, and matching input icons
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Faster level generation and improved performance
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Visual upgrades to environments and UI
Localization
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Russian and Finnish translations added
